The 3′→5′ exonuclease of DNA polymerase δ can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

Lignende værker

• The 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae
  af: Tran, Hiep T., et al.
  Udgivet: (1999)
• The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair
  af: Storici, Francesca, et al.
  Udgivet: (2002)
• The Multiple Biological Roles of the 3′→5′ Exonuclease of Saccharomyces cerevisiae DNA Polymerase δ Require Switching between the Polymerase and Exonuclease Domains
  af: Jin, Yong Hwan, et al.
  Udgivet: (2005)
• The GAN Exonuclease or the Flap Endonuclease Fen1 and RNase HII Are Necessary for Viability of Thermococcus kodakarensis
  af: Burkhart, Brett W., et al.
  Udgivet: (2017)
• Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t)
  af: Kokoska, Robert J., et al.
  Udgivet: (1998)