Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 controls (phase 1.) In phase 2, we genotyped the 15,008 highest-ranked SNPs in 2,057 Scottish cases and 2,111 controls. We the...

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সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Tenesa, Albert, Farrington, Susan M, Prendergast, James GD, Porteous, Mary E, Walker, Marion, Haq, Naila, Barnetson, Rebecca A, Theodoratou, Evropi, Cetnarskyj, Roseanne, Cartwright, Nicola, Semple, Colin, Clark, Andrew J, Reid, Fiona JL, Smith, Lorna A, Kavoussanakis, Kostas, Koessler, Thibaud, Pharoah, Paul DP, Buch, Stephan, Schafmayer, Clemens, Tepel, Jürgen, Schreiber, Stefan, Völzke, Henry, Schmidt, Carsten O, Hampe, Jochen, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Wilkening, Stefan, Canzian, Federico, Capella, Gabriel, Moreno, Victor, Deary, Ian J, Starr, John M, Tomlinson, Ian PM, Kemp, Zoe, Howarth, Kimberley, Carvajal-Carmona, Luis, Webb, Emily, Broderick, Peter, Vijayakrishnan, Jayaram, Houlston, Richard S, Rennert, Gad, Ballinger, Dennis, Rozek, Laura, Gruber, Stephen B, Matsuda, Koichi, Kidokoro, Tomohide, Nakamura, Yusuke, Zanke, Brent W, Greenwood, Celia MT, Rangrej, Jagadish, Kustra, Rafal, Montpetit, Alexandre, Hudson, Thomas J, Gallinger, Steven, Campbell, Harry, Dunlop, Malcolm G
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: 2008
বিষয়গুলি:
Article
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778004/
https://ncbi.nlm.nih.gov/pubmed/18372901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.133
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