DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers

PURPOSE: About 15% of colorectal cancers (CRCs) harbor microsatellite instability (MSI). MSI-associated gene expression changes have been identified in CRCs, but little overlap exists between signatures hindering an assessment of overall consistency. Little is known about the causes and downstream e...

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Main Authors: Jorissen, Robert N., Lipton, Lara, Gibbs, Peter, Chapman, Matthew, Desai, Jayesh, Jones, Ian T., Yeatman, Timothy J., East, Philip, Tomlinson, Ian P.M., Verspaget, Hein W., Aaltonen, Lauri A., Kruhøffer, Mogens, Ørntoft, Torben F., Andersen, Claus Lindbjerg, Sieber, Oliver M.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605660/
https://ncbi.nlm.nih.gov/pubmed/19088021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1431
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