ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer

Recently, a nonsense alteration Trp149Stop in the ARLTS1 gene was found more frequently in familial cancer cases vs. sporadic cancer patients and healthy controls. Here, the role of Trp149Stop or any other ARLTS1 germline variant was evaluated on breast, prostate, and colorectal cancer risk. The who...

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Main Authors: Siltanen, Sanna, Syrjäkoski, Kirsi, Fagerholm, Rainer, Ikonen, Tarja, Lipman, Peter, Mallott, Jacob, Holli, Kaija, Tammela, Teuvo LJ, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Aittomäki, Kristiina, Blomqvist, Carl, Bailey-Wilson, Joan E, Nevanlinna, Heli, Aaltonen, Lauri A, Schleutker, Johanna, Vahteristo, Pia
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404127/
https://ncbi.nlm.nih.gov/pubmed/18337727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.43
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