Contribution of ARLTS1 Cys148Arg (T442C) Variant with Prostate Cancer Risk and ARLTS1 Function in Prostate Cancer Cells

ARLTS1 is a recently characterized tumor suppressor gene at 13q14.3, a region frequently deleted in both sporadic and hereditary prostate cancer (PCa). ARLTS1 variants, especially Cys148Arg (T442C), increase susceptibility to different cancers, including PCa. In this study the role of Cys148Arg subs...

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Detalhes bibliográficos
Main Authors: Siltanen, Sanna, Wahlfors, Tiina, Schindler, Martin, Saramäki, Outi R., Mpindi, John Patrick, Latonen, Leena, Vessella, Robert L., Tammela, Teuvo L. J., Kallioniemi, Olli, Visakorpi, Tapio, Schleutker, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197657/
https://ncbi.nlm.nih.gov/pubmed/22028916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026595
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