Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior studies, with limited sample sizes, have failed to detect ass...

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發表在:Sci Rep
Main Authors: Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430741/
https://ncbi.nlm.nih.gov/pubmed/28432313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01199-0
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