Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Up to 86% of uterine leiomyomas harbour somatic mutations in mediator complex subunit 12 (MED12). These mutations have been associated with conventional histology, smaller tumour size, and larger number of tumours within the uterus. Prior studies, with limited sample sizes, have failed to detect ass...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Heinonen, Hanna-Riikka, Pasanen, Annukka, Heikinheimo, Oskari, Tanskanen, Tomas, Palin, Kimmo, Tolvanen, Jaana, Vahteristo, Pia, Sjöberg, Jari, Pitkänen, Esa, Bützow, Ralf, Mäkinen, Netta, Aaltonen, Lauri A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430741/
https://ncbi.nlm.nih.gov/pubmed/28432313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01199-0
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires