p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance

av Chen, Lindi, Tweddle, Deborah A.
Publicerad 2012

Cyclosporin neurotoxicity after chemotherapy

av Tweddle, Deborah A, Windebank, Kevin P, Hewson, Quentin Campbell, Yule, S Murray
Publicerad 1999

MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63

av Gamble, Laura D., Kees, Ursula R., Tweddle, Deborah A., Lunec, John
Publicerad 2011

Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma

av Southgate, Harriet E. D., Chen, Lindi, Curtin, Nicola J., Tweddle, Deborah A.
I publikationen Front Oncol (2020)

ATR Inhibition Potentiates PARP Inhibitor Cytotoxicity in High Risk Neuroblastoma Cell Lines by Multiple Mechanisms

av Southgate, Harriet E. D., Chen, Lindi, Tweddle, Deborah A., Curtin, Nicola J.
I publikationen Cancers (Basel) (2020)

A systematic review of re-induction chemotherapy for children with relapsed high-risk neuroblastoma

av Herd, Fiona, Basta, Nermine O., McNally, Richard J.Q., Tweddle, Deborah A.
I publikationen Eur J Cancer (2019)

p53 Cellular Localization and Function in Neuroblastoma : Evidence for Defective G(1) Arrest Despite WAF1 Induction in MYCN-Amplified Cells

av Tweddle, Deborah A., Malcolm, Archie J., Cole, Michael, Pearson, Andrew D.J., Lunec, John
Publicerad 2001

Temporal clustering of neuroblastic tumours in children and young adults from Northern England

av Muirhead, Colin R., Tweddle, Deborah A., Basta, Nermine O., McNally, Richard J. Q.
I publikationen Environ Health (2015)

A 7‐YEAR‐OLD BOY WITH MIDLINE CEREBELLAR MASS

av Ismail, Azzam, Lamont, Jayne M., Tweddle, Deborah A., Pearson, Andrew D., Clifford, Steven C., Ellison, David W.
I publikationen Brain Pathol (2006)

p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma

av Chen, Lindi, Iraci, Nunzio, Gherardi, Samuele, Gamble, Laura D., Wood, Katrina M., Perini, Giovanni, Lunec, John, Tweddle, Deborah A.
Publicerad 2010

Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma

av Chen, Lindi, Rousseau, Raphaël F., Middleton, Steven A., Nichols, Gwen L., Newell, David R., Lunec, John, Tweddle, Deborah A.
I publikationen Oncotarget (2015)

Identification of different ALK mutations in a pair of neuroblastoma cell lines established at diagnosis and relapse

av Chen, Lindi, Humphreys, Angharad, Turnbull, Lisa, Bellini, Angela, Schleiermacher, Gudrun, Salwen, Helen, Cohn, Susan L., Bown, Nick, Tweddle, Deborah A.
I publikationen Oncotarget (2016)

Pharmacokinetics and Safety of a Novel Oral Liquid Formulation of 13-cis Retinoic Acid in Children with Neuroblastoma: A Randomized Crossover Clinical Trial

av Veal, Gareth J., Tweddle, Deborah A., Visser, Johannes, Errington, Julie, Buck, Helen, Marange, Josephine, Moss, Jon, Joseph, Shiju, Mulla, Hussain
I publikationen Cancers (Basel) (2021)

Carboplatin therapeutic monitoring in preterm and full-term neonates

av Veal, Gareth J., Errington, Julie, Hayden, James, Hobin, David, Murphy, Dermot, Dommett, Rachel M., Tweddle, Deborah A., Jenkinson, Helen, Picton, Susan
I publikationen Eur J Cancer (2015)

Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis

av Carr-Wilkinson, Jane, Prathalingam, Nilendran, Pal, Deepali, Moad, Mohammad, Lee, Natalie, Sundaresh, Aishwarya, Forgham, Helen, James, Peter, Herbert, Mary, Lako, Majlinda, Tweddle, Deborah A.
I publikationen Stem Cells Int (2018)

Factors associated with recurrence and survival length following relapse in patients with neuroblastoma

av Basta, Nermine O, Halliday, Gail C, Makin, Guy, Birch, Jillian, Feltbower, Richard, Bown, Nick, Elliott, Martin, Moreno, Lucas, Barone, Giuseppe, Pearson, Andrew DJ, James, Peter W, Tweddle, Deborah A, McNally, Richard JQ
I publikationen Br J Cancer (2016)

Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma

av Chen, Lindi, Pastorino, Fabio, Berry, Philip, Bonner, Jennifer, Kirk, Calum, Wood, Katrina M., Thomas, Huw D., Zhao, Yan, Daga, Antonio, Veal, Gareth J., Lunec, John, Newell, David R., Ponzoni, Mirco, Tweddle, Deborah A.
I publikationen Int J Cancer (2019)

High frequency of p53/MDM2/p14(ARF) pathway abnormalities in relapsed neuroblastoma

av Carr-Wilkinson, Jane, O' Toole, Kieran, Wood, Katrina M., Challen, Christine C., Baker, Angela G., Board, Julian R., Evans, Laura, Cole, Michael, Cheung, Nai-Kong V., Boos, Joachim, Köhler, Gabriele, Leuschner, Ivo, Pearson, Andrew D.J., Lunec, John, Tweddle, Deborah A.
Publicerad 2010

Methyl-CpG-binding domain sequencing reveals a prognostic methylation signature in neuroblastoma

av Decock, Anneleen, Ongenaert, Maté, Cannoodt, Robrecht, Verniers, Kimberly, De Wilde, Bram, Laureys, Geneviève, Van Roy, Nadine, Berbegall, Ana P., Bienertova-Vasku, Julie, Bown, Nick, Clément, Nathalie, Combaret, Valérie, Haber, Michelle, Hoyoux, Claire, Murray, Jayne, Noguera, Rosa, Pierron, Gaelle, Schleiermacher, Gudrun, Schulte, Johannes H., Stallings, Ray L., Tweddle, Deborah A., De Preter, Katleen, Speleman, Frank, Vandesompele, Jo
I publikationen Oncotarget (2015)

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

av George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
I publikationen Eur J Cancer (2019)