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p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance

Neuroblastoma is the most common extra-cranial solid tumor of childhood. Despite significant advances, it currently still remains one of the most difficult childhood cancers to cure, with less than 40% of patients with high-risk disease being long-term survivors. MYCN is a proto-oncogene implicated...

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Detalhes bibliográficos
Main Authors: Chen, Lindi, Tweddle, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508619/
https://ncbi.nlm.nih.gov/pubmed/23226679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00173
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