NLRR1 Is a Potential Therapeutic Target in Neuroblastoma and MYCN-Driven Malignant Cancers

Receptor tyrosine kinases (RTKs) receive different modulation before transmitting proliferative signals. We previously identified neuronal leucine-rich repeat 1 (NLRR1) as a positive regulator of EGF and IGF-1 signals in high-risk neuroblastoma cells. Here, we show that NLRR1 is up-regulated in vari...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Takatori, Atsushi, Hossain, MD. Shamim, Ogura, Atsushi, Akter, Jesmin, Nakamura, Yohko, Nakagawara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279747/
https://ncbi.nlm.nih.gov/pubmed/34277416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.669667
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