NLRR1 Is a Potential Therapeutic Target in Neuroblastoma and MYCN-Driven Malignant Cancers

Receptor tyrosine kinases (RTKs) receive different modulation before transmitting proliferative signals. We previously identified neuronal leucine-rich repeat 1 (NLRR1) as a positive regulator of EGF and IGF-1 signals in high-risk neuroblastoma cells. Here, we show that NLRR1 is up-regulated in vari...

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Vydáno v:Front Oncol
Hlavní autoři: Takatori, Atsushi, Hossain, MD. Shamim, Ogura, Atsushi, Akter, Jesmin, Nakamura, Yohko, Nakagawara, Akira
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279747/
https://ncbi.nlm.nih.gov/pubmed/34277416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.669667
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