Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma

In neuroblastoma (NB), one of the most common paediatric solid tumours, activation of anaplastic lymphoma kinase (ALK) is often associated with poor outcomes. Although genetic studies have identified copy number alteration and nonsynonymous mutations of ALK, the regulatory mechanism of ALK signallin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Satoh, Shunpei, Takatori, Atsushi, Ogura, Atsushi, Kohashi, Kenichi, Souzaki, Ryota, Kinoshita, Yoshiaki, Taguchi, Tomoaki, Hossain, Md. Shamim, Ohira, Miki, Nakamura, Yohko, Nakagawara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015029/
https://ncbi.nlm.nih.gov/pubmed/27604320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32682
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