Neuronal leucine-rich repeat 1 negatively regulates anaplastic lymphoma kinase in neuroblastoma

In neuroblastoma (NB), one of the most common paediatric solid tumours, activation of anaplastic lymphoma kinase (ALK) is often associated with poor outcomes. Although genetic studies have identified copy number alteration and nonsynonymous mutations of ALK, the regulatory mechanism of ALK signallin...

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Publicat a:Sci Rep
Autors principals: Satoh, Shunpei, Takatori, Atsushi, Ogura, Atsushi, Kohashi, Kenichi, Souzaki, Ryota, Kinoshita, Yoshiaki, Taguchi, Tomoaki, Hossain, Md. Shamim, Ohira, Miki, Nakamura, Yohko, Nakagawara, Akira
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015029/
https://ncbi.nlm.nih.gov/pubmed/27604320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32682
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