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Role of Sex in the Therapeutic Targeting of p53 Circuitry

Sex profoundly affects cancer incidence and susceptibility to therapy, with sex hormones highly contributing to this disparity. Various studies and omics data suggest a relationship between sex and the oncosuppressor p53 circuitry, including its regulators MDM2 and MDM4. Association of this network...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Mancini, Francesca, Giorgini, Ludovica, Teveroni, Emanuela, Pontecorvi, Alfredo, Moretti, Fabiola
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298065/
https://ncbi.nlm.nih.gov/pubmed/34307167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.698946
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