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Role of Sex in the Therapeutic Targeting of p53 Circuitry
Sex profoundly affects cancer incidence and susceptibility to therapy, with sex hormones highly contributing to this disparity. Various studies and omics data suggest a relationship between sex and the oncosuppressor p53 circuitry, including its regulators MDM2 and MDM4. Association of this network...
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| Publié dans: | Front Oncol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298065/ https://ncbi.nlm.nih.gov/pubmed/34307167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.698946 |
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