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Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma

Despite intensive multimodal therapy, the survival rate for high risk neuroblastoma (HR-NB) remains <50%. Most cases initially respond to treatment but almost half will subsequently relapse with aggressive treatment resistant disease. Novel treatments exploiting the molecular pathology of NB and/...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Southgate, Harriet E. D., Chen, Lindi, Curtin, Nicola J., Tweddle, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145987/
https://ncbi.nlm.nih.gov/pubmed/32309213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00371
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