Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma

Telomeres play important roles in genome stability and cell proliferation. High risk neuroblastoma (HRNB), an aggressive childhood cancer, is especially reliant on telomere maintenance. Three recurrent genetic aberrations in HRNB (MYCN amplification, TERT re-arrangements, and ATRX mutations) are mut...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Yu, Eun Young, Cheung, Irene Y., Feng, Yi, Rabie, Mohamed O., Roboz, Gail J., Guzman, Monica L., Cheung, Nai-Kong V., Lue, Neal F.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2019
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535646/
https://ncbi.nlm.nih.gov/pubmed/31128432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.04.002
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