Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres

The Ku heterodimer serves in the initial step in repairing DNA double-strand breaks by the non-homologous end-joining pathway. Besides this key function, Ku also plays a role in other cellular processes including telomere maintenance. Inactivation of Ku can lead to DNA repair defects and telomere ab...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: de Sena-Tomás, Carmen, Yu, Eun Young, Calzada, Arturo, Holloman, William K., Lue, Neal F., Pérez-Martín, José
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344518/
https://ncbi.nlm.nih.gov/pubmed/25653166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv082
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars