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Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres
The Ku heterodimer serves in the initial step in repairing DNA double-strand breaks by the non-homologous end-joining pathway. Besides this key function, Ku also plays a role in other cellular processes including telomere maintenance. Inactivation of Ku can lead to DNA repair defects and telomere ab...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344518/ https://ncbi.nlm.nih.gov/pubmed/25653166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv082 |
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