The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage

DNA double-strand breaks (DSBs) are biologically one of the most important cellular lesions and possess varying degrees of chemical complexity. The notion that the repairability of more chemically complex DSBs is inefficient led to the concept that the extent of DSB complexity underlies the severity...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reynolds, Pamela, Anderson, Jennifer A., Harper, Jane V., Hill, Mark A., Botchway, Stanley W., Parker, Anthony W., O’Neill, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510491/
https://ncbi.nlm.nih.gov/pubmed/23012265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks879
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