Pharmacokinetics and Safety of a Novel Oral Liquid Formulation of 13-cis Retinoic Acid in Children with Neuroblastoma: A Randomized Crossover Clinical Trial

SIMPLE SUMMARY: The availability of a child-friendly drug formulation can be an important determinant of therapeutic success. 13-cis-retinoic acid (13-CRA) is a key component of high-risk neuroblastoma treatment protocols, and yet there is no such formulation available in any country worldwide. Typi...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Veal, Gareth J., Tweddle, Deborah A., Visser, Johannes, Errington, Julie, Buck, Helen, Marange, Josephine, Moss, Jon, Joseph, Shiju, Mulla, Hussain
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070696/
https://ncbi.nlm.nih.gov/pubmed/33919763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081868
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