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Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells
Recent data indicate that isomerisation to all-trans retinoic acid (ATRA) is the key mechanism underlying the favourable clinical properties of 13-cis retinoic acid (13cisRA) in the treatment of neuroblastoma. Retinoic acid (RA) metabolism is thought to contribute to resistance, and strategies to mo...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2361877/ https://ncbi.nlm.nih.gov/pubmed/15714209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602398 |
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