A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

BACKGROUND: For children with cancer, the clinical integration of precision medicine to enable predictive biomarker–based therapeutic stratification is urgently needed. METHODS: We have developed a hybrid-capture next-generation sequencing (NGS) panel, specifically designed to detect genetic alterat...

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Detalhes bibliográficos
Publicado no:Eur J Cancer
Main Authors: George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ltd 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839402/
https://ncbi.nlm.nih.gov/pubmed/31543384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2019.07.027
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