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Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis

BACKGROUND AND AIMS: Previous studies modelling human neural crest differentiation from stem cells have resulted in a low yield of sympathetic neurons. Our aim was to optimise a method for the differentiation of human embryonic stem cells (hESCs) to sympathetic neuron-like cells (SN) to model normal...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Carr-Wilkinson, Jane, Prathalingam, Nilendran, Pal, Deepali, Moad, Mohammad, Lee, Natalie, Sundaresh, Aishwarya, Forgham, Helen, James, Peter, Herbert, Mary, Lako, Majlinda, Tweddle, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236576/
https://ncbi.nlm.nih.gov/pubmed/30515222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4391641
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