Focus on fundamentals: achieving effective nanoparticle targeting

Por Tietjen, Gregory T., Bracaglia, Laura G., Saltzman, W. Mark, Pober, Jordan S.
Publicado no Trends Mol Med (2018)

Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes

Por Tietjen, Gregory T., DiRito, Jenna, Pober, Jordan S., Saltzman, W. Mark
Publicado no Nanomedicine (2017)

A holistic approach to targeting disease with polymer nanoparticles

Por Cheng, Christopher J., Tietjen, Gregory T., Saucier-Sawyer, Jennifer K., Saltzman, W. Mark
Publicado no Nat Rev Drug Discov (2015)

The future of marginal kidney repair in the context of normothermic machine perfusion

Por DiRito, Jenna R., Hosgood, Sarah A., Tietjen, Gregory T., Nicholson, Michael L.
Publicado no Am J Transplant (2018)

Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence

Por Gavrilov, Kseniya, Seo, Young-Eun, Tietjen, Gregory T., Cui, Jiajia, Cheng, Christopher J., Saltzman, W. Mark
Publicado no Proc Natl Acad Sci U S A (2015)

Sensitivity of Peripheral Membrane Proteins to the Membrane Context: A Case Study of Phosphatidylserine and the TIM Proteins

Por Kerr, Daniel, Tietjen, Gregory T., Gong, Zhiliang, Tajkhorshid, Emad, Adams, Erin J., Lee, Ka Yee C.
Publicado no Biochim Biophys Acta Biomembr (2018)

Tissue-Engineered Microvasculature to Reperfuse Isolated Renal Glomeruli

Por Chang, William Gee, Fornoni, Alessia, Tietjen, Gregory, Mendez, Julio J., Niklason, Laura E., Saltzman, W. Mark, Pober, Jordan S.
Publicado no Tissue Eng Part A (2015)

Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium

Por Lysyy, Taras, Bracaglia, Laura G., Qin, Lingfeng, Albert, Claire, Pober, Jordan S., Tellides, George, Saltzman, W. Mark, Tietjen, Gregory T.
Publicado no Bioeng Transl Med (2020)

High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents

Por Bracaglia, Laura G., Piotrowski-Daspit, Alexandra S., Lin, Chun-Yu, Moscato, Zoe M., Wang, Yongheng, Tietjen, Gregory T., Saltzman, W. Mark
Publicado no Proc Natl Acad Sci U S A (2020)

Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells

Por Cui, Jiajia, Qin, Lingfeng, Zhang, Junwei, Abrahimi, Parwiz, Li, Hong, Li, Guangxin, Tietjen, Gregory T., Tellides, George, Pober, Jordan S., Mark Saltzman, W.
Publicado no Nat Commun (2017)

Surface chemistry governs cellular tropism of nanoparticles in the brain

Por Song, Eric, Gaudin, Alice, King, Amanda R., Seo, Young-Eun, Suh, Hee-Won, Deng, Yang, Cui, Jiajia, Tietjen, Gregory T., Huttner, Anita, Saltzman, W. Mark
Publicado no Nat Commun (2017)

A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery

Por Jiang, Yuhang, Gaudin, Alice, Zhang, Junwei, Agarwal, Tushar, Song, Eric, Kauffman, Amy C., Tietjen, Gregory T., Wang, Yongheng, Jiang, Zhaozhong, Cheng, Christopher J., Saltzman, W. Mark
Publicado no Biomaterials (2018)

Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery

Por Jiang, Yuhang, Lu, Qiao, Wang, Yongheng, Xu, Emily, Ho, Alison, Singh, Priya, Wang, Yifei, Jiang, Zhaozhong, Yang, Fan, Tietjen, Gregory T., Cresswell, Peter, Saltzman, W. Mark
Publicado no Nano Lett (2020)

Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro

Por Kosyakova, Natalia, Kao, Derek D., Figetakis, Maria, López-Giráldez, Francesc, Spindler, Susann, Graham, Morven, James, Kevin J., Won Shin, Jee, Liu, Xinran, Tietjen, Gregory T., Pober, Jordan S., Chang, William G.
Publicado no NPJ Regen Med (2020)

Coupling X-Ray Reflectivity and In Silico Binding to Yield Dynamics of Membrane Recognition by Tim1

Por Tietjen, Gregory T., Baylon, Javier L., Kerr, Daniel, Gong, Zhiliang, Henderson, J. Michael, Heffern, Charles T.R., Meron, Mati, Lin, Binhua, Schlossman, Mark L., Adams, Erin J., Tajkhorshid, Emad, Lee, Ka Yee C.
Publicado no Biophys J (2017)

Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1

Por Liu, Rebecca, Merola, Jonathan, Manes, Thomas D., Qin, Lingfeng, Tietjen, Gregory T., López-Giráldez, Francesc, Broecker, Verena, Fang, Caodi, Xie, Catherine, Chen, Ping-Min, Kirkiles-Smith, Nancy C., Jane-Wit, Dan, Pober, Jordan S.
Publicado no JCI Insight (2018)

Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver

Por Cui, Jiajia, Piotrowski-Daspit, Alexandra S., Zhang, Junwei, Shao, Mingjie, Bracaglia, Laura G., Utsumi, Teruo, Seo, Young-Eun, DiRito, Jenna, Song, Eric, Wu, Christine, Inada, Asuka, Tietjen, Gregory T., Pober, Jordan S., Iwakiri, Yasuko, Saltzman, W. Mark
Publicado no J Control Release (2019)

Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression

Por Merola, Jonathan, Reschke, Melanie, Pierce, Richard W., Qin, Lingfeng, Spindler, Susann, Baltazar, Tania, Manes, Thomas D., Lopez-Giraldez, Francesc, Li, Guangxin, Bracaglia, Laura G., Xie, Catherine, Kirkiles-Smith, Nancy, Saltzman, W. Mark, Tietjen, Gregory T., Tellides, George, Pober, Jordan S.
Publicado no JCI Insight (2019)

Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4

Por Tietjen, Gregory T., Gong, Zhiliang, Chen, Chiu-Hao, Vargas, Ernesto, Crooks, James E., Cao, Kathleen D., Heffern, Charles T. R., Henderson, J. Michael, Meron, Mati, Lin, Binhua, Roux, Benoît, Schlossman, Mark L., Steck, Theodore L., Lee, Ka Yee C., Adams, Erin J.
Publicado em 2014

ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes

Por Fang, Caodi, Manes, Thomas D., Liu, Lufang, Liu, Kevin, Qin, Lingfeng, Li, Guangxin, Tobiasova, Zuzana, Kirkiles-Smith, Nancy C., Patel, Manal, Merola, Jonathan, Fu, Whitney, Liu, Rebecca, Xie, Catherine, Tietjen, Gregory T., Nigrovic, Peter A., Tellides, George, Pober, Jordan S., Jane-wit, Dan
Publicado no Nat Commun (2019)