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High-throughput quantitative microscopy-based half-life measurements of intravenously injected agents

Accurate analysis of blood concentration and circulation half-life is an important consideration for any intravenously administered agent in preclinical development or for therapeutic application. However, the currently available tools to measure these parameters are laborious, expensive, and ineffi...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Bracaglia, Laura G., Piotrowski-Daspit, Alexandra S., Lin, Chun-Yu, Moscato, Zoe M., Wang, Yongheng, Tietjen, Gregory T., Saltzman, W. Mark
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035491/
https://ncbi.nlm.nih.gov/pubmed/32015123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915450117
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