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Surface chemistry governs cellular tropism of nanoparticles in the brain

Nanoparticles are of long-standing interest for the treatment of neurological diseases such as glioblastoma. Most past work focused on methods to introduce nanoparticles into the brain, suggesting that reaching the brain interstitium will be sufficient to ensure therapeutic efficacy. However, optimi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Song, Eric, Gaudin, Alice, King, Amanda R., Seo, Young-Eun, Suh, Hee-Won, Deng, Yang, Cui, Jiajia, Tietjen, Gregory T., Huttner, Anita, Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454541/
https://ncbi.nlm.nih.gov/pubmed/28524852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15322
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