Nanoparticle-mediated intratumoral inhibition of miR-21 for improved survival in glioblastoma

Glioblastoma (GBM) is the most common and deadly form of malignant brain tumor in the United States, and current therapies fail to provide significant improvement in survival. Local delivery of nanoparticles is a promising therapeutic strategy that bypasses the blood-brain barrier, minimizes systemi...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Seo, Young-Eun, Suh, Hee-Won, Bahal, Raman, Josowitz, Alexander, Zhang, Junwei, Song, Eric, Cui, Jiajia, Noorbakhsh, Seth, Jackson, Christopher, Bu, Tom, Piotrowski-Daspit, Alexandra, Bindra, Ranjit, Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451656/
https://ncbi.nlm.nih.gov/pubmed/30802686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2019.02.016
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