Distribution of Polymer Nanoparticles by Convection-Enhanced Delivery to Brain Tumors

Glioblastoma multiforme (GBM) is a fatal brain tumor characterized by infiltration beyond the margins of the main tumor mass and local recurrence after surgery. The blood-brain barrier (BBB) poses the most significant hurdle to brain tumor treatment. Convection-enhanced delivery (CED) allows for loc...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Saucier-Sawyer, Jennifer K., Seo, Young-Eun, Gaudin, Alice, Quijano, Elias, Song, Eric, Sawyer, Andrew J., Deng, Yang, Huttner, Anita, Saltzman, W. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893898/
https://ncbi.nlm.nih.gov/pubmed/27063424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.04.006
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