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Systemic Delivery of Blood-Brain Barrier Targeted Polymeric Nanoparticles Enhances Delivery to Brain Tissue

Delivery of therapeutic agents to the central nervous system is a significant challenge, hindering progress in the treatment of diseases such as glioblastoma. Due to the presence of the blood-brain barrier (BBB), therapeutic agents do not readily transverse the brain endothelium to enter the parench...

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Detalhes bibliográficos
Publicado no:J Drug Target
Main Authors: Saucier-Sawyer, Jennifer K., Deng, Yang, Seo, Young-Eun, Cheng, Christopher J., Zhang, Junwei, Quijano, Elias, Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860350/
https://ncbi.nlm.nih.gov/pubmed/26453169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2015.1065833
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