Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities


מאת Quijano, Elias, Bahal, Raman, Ricciardi, Adele, Saltzman, W. Mark, Glazer, Peter M.
הוצא לאור ב Yale J Biol Med (2017)

Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing

מאת Ricciardi, Adele S., Quijano, Elias, Putman, Rachael, Saltzman, W. Mark, Glazer, Peter M.
הוצא לאור ב Molecules (2018)

Poly(lactic-co-glycolic acid) Nanoparticle Delivery of Peptide Nucleic Acids In Vivo

מאת Oyaghire, Stanley N., Quijano, Elias, Piotrowski-Daspit, Alexandra S., Saltzman, W. Mark, Glazer, Peter M.
הוצא לאור ב Methods Mol Biol (2020)

Antisense Oligonucleotides: An Emerging Area in Drug Discovery and Development

מאת Dhuri, Karishma, Bechtold, Clara, Quijano, Elias, Pham, Ha, Gupta, Anisha, Vikram, Ajit, Bahal, Raman
הוצא לאור ב J Clin Med (2020)

Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

מאת Economos, Nicholas G., Oyaghire, Stanley, Quijano, Elias, Ricciardi, Adele S., Saltzman, W. Mark, Glazer, Peter M.
הוצא לאור ב Molecules (2020)

Degradable Bioadhesive Nanoparticles for Prolonged Intravaginal Delivery and Retention of Elvitegravir

מאת Mohideen, Muneeb, Quijano, Elias, Song, Eric, Deng, Yang, Panse, Gauri, Zhang, Wei, Clark, Meredith R., Saltzman, W. Mark
הוצא לאור ב Biomaterials (2017)

Systemic Delivery of Blood-Brain Barrier Targeted Polymeric Nanoparticles Enhances Delivery to Brain Tissue

מאת Saucier-Sawyer, Jennifer K., Deng, Yang, Seo, Young-Eun, Cheng, Christopher J., Zhang, Junwei, Quijano, Elias, Saltzman, W. Mark
הוצא לאור ב J Drug Target (2015)

Optimizing Biodegradable Nanoparticle Size for Tissue-Specific Delivery

מאת Mandl, Hanna K., Quijano, Elias, Suh, Hee Won, Sparago, Emily, Oeck, Sebastian, Grun, Molly, Glazer, Peter M., Saltzman, W. Mark
הוצא לאור ב J Control Release (2019)

Surface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery

מאת Fields, Rachel J., Cheng, Christopher J., Quijano, Elias, Weller, Caroline, Kristofik, Nina, Duong, Nha, Hoimes, Christopher, Egan, Marie E., Saltzman, W. Mark
יצא לאור 2012

Distribution of Polymer Nanoparticles by Convection-Enhanced Delivery to Brain Tumors

מאת Saucier-Sawyer, Jennifer K., Seo, Young-Eun, Gaudin, Alice, Quijano, Elias, Song, Eric, Sawyer, Andrew J., Deng, Yang, Huttner, Anita, Saltzman, W. Mark
הוצא לאור ב J Control Release (2016)

Modified Poly(lactic-co-glycolic acid) Nanoparticles for Enhanced Cellular Uptake and Gene Editing in the Lung

מאת Fields, Rachel J., Quijano, Elias, McNeer, Nicole Ali, Caputo, Christina, Bahal, Raman, Anandalingam, Kavi, Egan, Marie E., Glazer, Peter M., Saltzman, W. Mark
הוצא לאור ב Adv Healthc Mater (2014)

Fas Ligand and Nitric Oxide Combination to Control Smooth Muscle Growth while Sparing Endothelium

מאת Kural, Mehmet H., Wang, Juan, Gui, Liqiong, Yuan, Yifan, Li, Guangxin, Leiby, Katherine L., Quijano, Elias, Tellides, George, Saltzman, W. Mark, Niklason, Laura E.
הוצא לאור ב Biomaterials (2019)

From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection

מאת Kudalkar, Shalley N., Beloor, Jagadish, Quijano, Elias, Spasov, Krasimir A., Lee, Won-Gil, Cisneros, José A., Saltzman, W. Mark, Kumar, Priti, Jorgensen, William L., Anderson, Karen S.
הוצא לאור ב Proc Natl Acad Sci U S A (2018)

Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection

מאת Kudalkar, Shalley N., Beloor, Jagadish, Quijano, Elias, Spasov, Krasimir A., Lee, Won-Gil, Cisneros, José A., Saltzman, W. Mark, Kumar, Priti, Jorgensen, William L., Anderson, Karen S.
הוצא לאור ב Proc Natl Acad Sci U S A (2018)

Single-Stranded γPNAs for In Vivo Site-Specific Genome Editing via Watson-Crick Recognition

מאת Bahal, Raman, Quijano, Elias, McNeer, Nicole Ali, Liu, Yanfeng, Bhunia, Dinesh C., López-Giráldez, Francesco, Fields, Rachel J., Saltzman, W. Mark, Ly, Danith H., Glazer, Peter M.
הוצא לאור ב Curr Gene Ther (2014)

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

מאת Gupta, Anisha, Quijano, Elias, Liu, Yanfeng, Bahal, Raman, Scanlon, Susan E., Song, Eric, Hsieh, Wei-Che, Braddock, Demetrios E., Ly, Danith H., Saltzman, W. Mark, Glazer, Peter M.
הוצא לאור ב Mol Ther Nucleic Acids (2017)

Structural and Pharmacological Evaluation of a Novel Non-nucleoside Reverse Transcriptase Inhibitor as a Promising Long Acting Nanoformulation for Treating HIV

מאת Kudalkar, Shalley N., Ullah, Irfan, Bertoletti, Nicole, Mandl, Hanna K., Cisneros, José A., Beloor, Jagadish, Chan, Albert H., Quijano, Elias, Saltzman, W. Mark, Jorgensen, William L., Kumar, Priti, Anderson, Karen S.
הוצא לאור ב Antiviral Res (2019)

Correction of F508del CFTR in airway epithelium using nanoparticles delivering triplex-forming PNAs

מאת McNeer, Nicole Ali, Anandalingam, Kavitha, Fields, Rachel J., Caputo, Christina, Kopic, Sascha, Gupta, Anisha, Quijano, Elias, Polikoff, Lee, Kong, Yong, Bahal, Raman, Geibel, John P, Glazer, Peter M., Saltzman, W. Mark, Egan, Marie E.
הוצא לאור ב Nat Commun (2015)

In utero nanoparticle delivery for site-specific genome editing

מאת Ricciardi, Adele S., Bahal, Raman, Farrelly, James S., Quijano, Elias, Bianchi, Anthony H., Luks, Valerie L., Putman, Rachael, López-Giráldez, Francesc, Coşkun, Süleyman, Song, Eric, Liu, Yanfeng, Hsieh, Wei-Che, Ly, Danith H., Stitelman, David H., Glazer, Peter M., Saltzman, W. Mark
הוצא לאור ב Nat Commun (2018)

In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery

מאת Bahal, Raman, Ali McNeer, Nicole, Quijano, Elias, Liu, Yanfeng, Sulkowski, Parker, Turchick, Audrey, Lu, Yi-Chien, Bhunia, Dinesh C., Manna, Arunava, Greiner, Dale L., Brehm, Michael A., Cheng, Christopher J., López-Giráldez, Francesc, Ricciardi, Adele, Beloor, Jagadish, Krause, Diane S., Kumar, Priti, Gallagher, Patrick G., Braddock, Demetrios T., Mark Saltzman, W., Ly, Danith H., Glazer, Peter M.
הוצא לאור ב Nat Commun (2016)