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Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

Unusual nucleic acid structures are salient triggers of endogenous repair and can occur in sequence-specific contexts. Peptide nucleic acids (PNAs) rely on these principles to achieve non-enzymatic gene editing. By forming high-affinity heterotriplex structures within the genome, PNAs have been used...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Economos, Nicholas G., Oyaghire, Stanley, Quijano, Elias, Ricciardi, Adele S., Saltzman, W. Mark, Glazer, Peter M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037966/
https://ncbi.nlm.nih.gov/pubmed/32046275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030735
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