Modified Poly(lactic-co-glycolic acid) Nanoparticles for Enhanced Cellular Uptake and Gene Editing in the Lung

Modified nanoparticles composed of a blend between poly(β-amino ester) (PBAE) and poly(lactic-co-glycolic acid) (PLGA), surface coated with cell-penetrating peptides (CPPs), have previously shown promise in gene delivery. In this study, we sought to evaluate pulmonary cellular uptake of these modifi...

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Publicado en:Adv Healthc Mater
Main Authors: Fields, Rachel J., Quijano, Elias, McNeer, Nicole Ali, Caputo, Christina, Bahal, Raman, Anandalingam, Kavi, Egan, Marie E., Glazer, Peter M., Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339402/
https://ncbi.nlm.nih.gov/pubmed/25156908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400355
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