POLYMER DELIVERY SYSTEMS FOR SITE-SPECIFIC GENOME EDITING

Triplex-forming peptide nucleic acids (PNAs) can be used to coordinate the recombination of short 50–60 bp “donor DNA” fragments into genomic DNA, resulting in site-specific correction of genetic mutations or the introduction of advantageous genetic modifications. Site-specific gene editing in hemat...

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Détails bibliographiques
Auteurs principaux: McNeer, Nicole Ali, Schleifman, Erica B., Glazer, Peter M., Saltzman, W. Mark
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176956/
https://ncbi.nlm.nih.gov/pubmed/21620910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.05.011
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