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PEGylated squalenoyl-gemcitabine nanoparticles for the treatment of glioblastoma
New treatments for glioblastoma multiforme (GBM) are desperately needed, as GBM prognosis remains poor, mainly due to treatment resistance, poor distribution of therapeutics in the tumor tissue, and fast metabolism of chemotherapeutic drugs in the brain extracellular space. Convection-enhanced deliv...
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| Veröffentlicht in: | Biomaterials |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072177/ https://ncbi.nlm.nih.gov/pubmed/27521616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.07.037 |
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