A Scalable Method for Squalenoylation and Assembly of Multifunctional (64)Cu-Labeled Squalenoylated Gemcitabine Nanoparticles

Squalenoylation of gemcitabine, a front-line therapy for pancreatic cancer, allows for improved cellular-level and system-wide drug delivery. The established methods to conjugate squalene to gemcitabine and to form nanoparticles (NPs) with the squalenoylated gemcitabine (SqGem) conjugate are cumbers...

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Dettagli Bibliografici
Pubblicato in:Nanotheranostics
Autori principali: Tucci, Samantha T., Seo, Jai W., Kakwere, Hamilton, Kheirolomoom, Azadeh, Ingham, Elizabeth S., Mahakian, Lisa M., Tam, Sarah, Tumbale, Spencer, Baikoghli, Mo, Cheng, R. Holland, Ferrara, Katherine W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170330/
https://ncbi.nlm.nih.gov/pubmed/30324084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.26969
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