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Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1
Early acute rejection of human allografts is mediated by circulating alloreactive host effector memory T cells (T(EM)). T(EM) infiltration typically occurs across graft postcapillary venules and involves sequential interactions with graft-derived endothelial cells (ECs) and pericytes (PCs). While th...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5922286/ https://ncbi.nlm.nih.gov/pubmed/29515027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97881 |
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