Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver

Degradable poly(amine-co-ester) (PACE) terpolymers hold tremendous promise for siRNA delivery because these materials can be formulated into delivery vehicles with highly efficient siRNA encapsulation, providing effective knockdown with low toxicity. Here, we demonstrate that PACE nanoparticles (NPs...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Cui, Jiajia, Piotrowski-Daspit, Alexandra S., Zhang, Junwei, Shao, Mingjie, Bracaglia, Laura G., Utsumi, Teruo, Seo, Young-Eun, DiRito, Jenna, Song, Eric, Wu, Christine, Inada, Asuka, Tietjen, Gregory T., Pober, Jordan S., Iwakiri, Yasuko, Saltzman, W. Mark
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613984/
https://ncbi.nlm.nih.gov/pubmed/31054286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.044
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