Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver

Degradable poly(amine-co-ester) (PACE) terpolymers hold tremendous promise for siRNA delivery because these materials can be formulated into delivery vehicles with highly efficient siRNA encapsulation, providing effective knockdown with low toxicity. Here, we demonstrate that PACE nanoparticles (NPs...

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Publicado en:J Control Release
Autores principales: Cui, Jiajia, Piotrowski-Daspit, Alexandra S., Zhang, Junwei, Shao, Mingjie, Bracaglia, Laura G., Utsumi, Teruo, Seo, Young-Eun, DiRito, Jenna, Song, Eric, Wu, Christine, Inada, Asuka, Tietjen, Gregory T., Pober, Jordan S., Iwakiri, Yasuko, Saltzman, W. Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613984/
https://ncbi.nlm.nih.gov/pubmed/31054286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.044
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