Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver

Degradable poly(amine-co-ester) (PACE) terpolymers hold tremendous promise for siRNA delivery because these materials can be formulated into delivery vehicles with highly efficient siRNA encapsulation, providing effective knockdown with low toxicity. Here, we demonstrate that PACE nanoparticles (NPs...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Cui, Jiajia, Piotrowski-Daspit, Alexandra S., Zhang, Junwei, Shao, Mingjie, Bracaglia, Laura G., Utsumi, Teruo, Seo, Young-Eun, DiRito, Jenna, Song, Eric, Wu, Christine, Inada, Asuka, Tietjen, Gregory T., Pober, Jordan S., Iwakiri, Yasuko, Saltzman, W. Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613984/
https://ncbi.nlm.nih.gov/pubmed/31054286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.04.044
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