A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery

Gene delivery is known to be a complicated multi-step biological process. It has been observed that subtle differences in the structure and properties of polymeric materials used for gene delivery can lead to dramatic differences in transfection efficiency. Therefore, screening of properties is pivo...

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Veröffentlicht in:Biomaterials
Hauptverfasser: Jiang, Yuhang, Gaudin, Alice, Zhang, Junwei, Agarwal, Tushar, Song, Eric, Kauffman, Amy C., Tietjen, Gregory T., Wang, Yongheng, Jiang, Zhaozhong, Cheng, Christopher J., Saltzman, W. Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038928/
https://ncbi.nlm.nih.gov/pubmed/29879653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.05.043
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