A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery

Gene delivery is known to be a complicated multi-step biological process. It has been observed that subtle differences in the structure and properties of polymeric materials used for gene delivery can lead to dramatic differences in transfection efficiency. Therefore, screening of properties is pivo...

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Publicado no:Biomaterials
Main Authors: Jiang, Yuhang, Gaudin, Alice, Zhang, Junwei, Agarwal, Tushar, Song, Eric, Kauffman, Amy C., Tietjen, Gregory T., Wang, Yongheng, Jiang, Zhaozhong, Cheng, Christopher J., Saltzman, W. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038928/
https://ncbi.nlm.nih.gov/pubmed/29879653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.05.043
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