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Enzyme-synthesized Poly(amine-co-esters) as Non-viral Vectors for Gene Delivery

A family of biodegradable poly(amine-co-esters) was synthesized in one step via enzymatic copolymerization of diesters with amino-substituted diols. Diesters of length C(4)–C(12) (i.e., from succinate to dodecanedioate) were successfully copolymerized with diethanolamines with either an alkyl (methy...

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Détails bibliographiques
Auteurs principaux: Liu, Jie, Jiang, Zhaozhong, Zhou, Jiangbing, Zhang, Shengmin, Saltzman, W. Mark
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080021/
https://ncbi.nlm.nih.gov/pubmed/21171165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32994
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