Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

Por Naidoo, Kewreshini K., Ngubane, Ayanda, Gaza, Pedzisai, Moodley, Amber, Ndung'u, Thumbi, Thobakgale, Christina F.
Publicado no Front Immunol (2019)

The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans

Por Naidoo, Kewreshini K., Shangase, Zesuliwe B., Rashid, Tabassum, Ngubane, Ayanda, Ismail, Nasreen, Ndung’u, Thumbi, Thobakgale, Christina F.
Publicado no PLoS One (2020)

Replicative Capacity of Human Immunodeficiency Virus Type 1 Transmitted from Mother to Child Is Associated with Pediatric Disease Progression Rate

Por Prado, Julia G., Prendergast, Andrew, Thobakgale, Christina, Molina, Claudia, Tudor-Williams, Gareth, Ndung'u, Thumbi, Walker, Bruce D., Goulder, Philip
Publicado em 2010

Interleukin 1-beta (IL-1β) production by innate cells following TLR stimulation correlates with TB recurrence in ART-treated HIV infected patients

Por Thobakgale, Christina, Naidoo, Kewreshini, McKinnon, Lyle R., Werner, Lise, Samsunder, Natasha, Karim, Salim Abdool, Ndung’u, Thumbi, Altfeld, Marcus, Naidoo, Kogieleum
Publicado no J Acquir Immune Defic Syndr (2017)

HIV-1 Evades a Gag Mutation that Abrogates KIR Binding and Disinhibits NK Cells in Infected Individuals with KIR2DL2(+)/HLA-C*03:04(+) Genotype

Por Ziegler, Maja C., Naidoo, Kewreshini, Chapel, Anais, Nkotwana, Sindiswa, Mann, Jaclyn, Mncube, Zenele, Ismael, Nasreen, Goulder, Philip, Ndung’u, Thumbi, Altfeld, Marcus, Thobakgale, Christina F.
Publicado no AIDS (2021)

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

Por Mkhwanazi, Nompumelelo, Thobakgale, Christina F., van der Stok, Mary, Reddy, Shabashini, Mncube, Zenele, Chonco, Fundisiwe, Walker, Bruce D., Altfeld, Marcus, Goulder, Philip J.R., Ndung'u, Thumbi
Publicado em 2010

Short Communication: CD8(+) T Cell Polyfunctionality Profiles in Progressive and Nonprogressive Pediatric HIV Type 1 Infection

Por Thobakgale, Christina F., Streeck, Hendrik, Mkhwanazi, Nompumelelo, Mncube, Zenele, Maphumulo, Lungile, Chonco, Fundisiwe, Prendergast, Andrew, Tudor-Williams, Gareth, Walker, Bruce D., Goulder, Philip J.R., Altfeld, Marcus, Ndung'u, Thumbi
Publicado em 2011

Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection

Por Thobakgale, Christina F., Fadda, Lena, Lane, Kimberly, Toth, Ildiko, Pereyra, Florencia, Bazner, Suzane, Ndung'u, Thumbi, Walker, Bruce D., Rosenberg, Eric S., Alter, Galit, Carrington, Mary, Allen, Todd M., Altfeld, Marcus
Publicado em 2012

Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1

Por Martinez-Picado, Javier, Prado, Julia G., Fry, Elizabeth E., Pfafferott, Katja, Leslie, Alasdair, Chetty, Senica, Thobakgale, Christina, Honeyborne, Isobel, Crawford, Hayley, Matthews, Philippa, Pillay, Tilly, Rousseau, Christine, Mullins, James I., Brander, Christian, Walker, Bruce D., Stuart, David I., Kiepiela, Photini, Goulder, Philip
Publicado em 2006

Immunodominant HIV-1 Cd4+ T Cell Epitopes in Chronic Untreated Clade C HIV-1 Infection

Por Ramduth, Danni, Day, Cheryl L., Thobakgale, Christina F., Mkhwanazi, Nompumelelo P., de Pierres, Chantal, Reddy, Sharon, van der Stok, Mary, Mncube, Zenele, Nair, Kriebashne, Moodley, Eshia S., Kaufmann, Daniel E., Streeck, Hendrik, Coovadia, Hoosen M., Kiepiela, Photini, Goulder, Philip J. R., Walker, Bruce D.
Publicado em 2009

Human Immunodeficiency Virus-Specific CD8(+) T-Cell Activity Is Detectable from Birth in the Majority of In Utero-Infected Infants

Por Thobakgale, Christina F., Ramduth, Dhanwanthie, Reddy, Sharon, Mkhwanazi, Nompumelelo, de Pierres, Chantal, Moodley, Eshia, Mphatswe, Wendy, Blanckenberg, Natasha, Cengimbo, Ayanda, Prendergast, Andrew, Tudor-Williams, Gareth, Dong, Krista, Jeena, Prakash, Kindra, Gupreet, Bobat, Raziya, Coovadia, Hoosen, Kiepiela, Photini, Walker, Bruce D., Goulder, Philip J. R.
Publicado em 2007

Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

Por Thobakgale, Christina F., Prendergast, Andrew, Crawford, Hayley, Mkhwanazi, Nompumelelo, Ramduth, Danni, Reddy, Sharon, Molina, Claudia, Mncube, Zenele, Leslie, Alasdair, Prado, Julia, Chonco, Fundi, Mphatshwe, Wendy, Tudor-Williams, Gareth, Jeena, Prakash, Blanckenberg, Natasha, Dong, Krista, Kiepiela, Photini, Coovadia, Hoosen, Ndung'u, Thumbi, Walker, Bruce D., Goulder, Philip J. R.
Publicado em 2009

Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

Por Thobakgale, Christina F., Prendergast, Andrew, Crawford, Hayley, Mkhwanazi, Nompumelelo, Ramduth, Danni, Reddy, Sharon, Molina, Claudia, Mncube, Zenele, Leslie, Alasdair, Prado, Julia, Chonco, Fundi, Mphatshwe, Wendy, Tudor-Williams, Gareth, Jeena, Prakash, Blanckenberg, Natasha, Dong, Krista, Kiepiela, Photini, Coovadia, Hoosen, Ndung'u, Thumbi, Walker, Bruce D., Goulder, Philip J. R.
Publicado no J Virol (2015)

Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection

Por Adland, Emily, Paioni, Paolo, Thobakgale, Christina, Laker, Leana, Mori, Luisa, Muenchhoff, Maximilian, Csala, Anna, Clapson, Margaret, Flynn, Jacquie, Novelli, Vas, Hurst, Jacob, Naidoo, Vanessa, Shapiro, Roger, Huang, Kuan-Hsiang Gary, Frater, John, Prendergast, Andrew, Prado, Julia G., Ndung’u, Thumbi, Walker, Bruce D., Carrington, Mary, Jooste, Pieter, Goulder, Philip J. R.
Publicado no PLoS Pathog (2015)

Impact of select immunologic and virologic biomarkers on CD4 decline in chronic HIV-1 subtype C infection: Results from Sinikithemba longitudinal population-based cohort, Durban, S...

Por Brumme, Zabrina, Wang, Bingxia, Nair, Kriebashne, Brumme, Chanson, de Pierres, Chantal, Reddy, Shabashini, Julg, Boris, Moodley, Eshia, Thobakgale, Christina, Lu, Zhigang, van der Stok, Mary, Bishop, Karen, Mncube, Zenele, Chonco, Fundisiwe, Yuki, Yuko, Frahm, Nicole, Brander, Christian, Carrington, Mary, Freedberg, Kenneth, Kiepiela, Photini, Goulder, Philip, Walker, Bruce, Ndung’u, Thumbi, Losina, Elena
Publicado em 2009

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA

Por Leslie, Alasdair, Kavanagh, Daniel, Honeyborne, Isobella, Pfafferott, Katja, Edwards, Charles, Pillay, Tilly, Hilton, Louise, Thobakgale, Christina, Ramduth, Danni, Draenert, Rika, Le Gall, Sylvie, Luzzi, Graz, Edwards, Anne, Brander, Christian, Sewell, Andrew K., Moore, Sarah, Mullins, James, Moore, Corey, Mallal, Simon, Bhardwaj, Nina, Yusim, Karina, Phillips, Rodney, Klenerman, Paul, Korber, Bette, Kiepiela, Photini, Walker, Bruce, Goulder, Philip
Publicado em 2005

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South...

Por Hölzemer, Angelique, Thobakgale, Christina F., Jimenez Cruz, Camilo A., Garcia-Beltran, Wilfredo F., Carlson, Jonathan M., van Teijlingen, Nienke H., Mann, Jaclyn K., Jaggernath, Manjeetha, Kang, Seung-gu, Körner, Christian, Chung, Amy W., Schafer, Jamie L., Evans, David T., Alter, Galit, Walker, Bruce D., Goulder, Philip J., Carrington, Mary, Hartmann, Pia, Pertel, Thomas, Zhou, Ruhong, Ndung’u, Thumbi, Altfeld, Marcus
Publicado no PLoS Med (2015)

Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape

Por Leitman, Ellen M., Thobakgale, Christina F., Adland, Emily, Ansari, M. Azim, Raghwani, Jayna, Prendergast, Andrew J., Tudor-Williams, Gareth, Kiepiela, Photini, Hemelaar, Joris, Brener, Jacqui, Tsai, Ming-Han, Mori, Masahiko, Riddell, Lynn, Luzzi, Graz, Jooste, Pieter, Ndung’u, Thumbi, Walker, Bruce D., Pybus, Oliver G., Kellam, Paul, Naranbhai, Vivek, Matthews, Philippa C., Gall, Astrid, Goulder, Philip J.R.
Publicado no J Exp Med (2017)

NON-PROGRESSING HIV-INFECTED CHILDREN SHARE FUNDAMENTAL IMMUNOLOGICAL FEATURES OF NON-PATHOGENIC SIV INFECTION

Por Muenchhoff, Maximilian, Adland, Emily, Karimanzira, Owen, Crowther, Carol, Pace, Matthew, Csala, Anna, Leitman, Ellen, Moonsamy, Angeline, McGregor, Callum, Hurst, Jacob, Groll, Andreas, Mori, Masahiko, Sinmyee, Smruti, Thobakgale, Christina, Tudor-Williams, Gareth, Prendergast, Andrew J, Kloverpris, Henrik, Roider, Julia, Leslie, Alasdair, Shingadia, Delane, Brits, Thea, Daniels, Samantha, Frater, John, Willberg, Christian B, Walker, Bruce D, Ndung’u, Thumbi, Jooste, Pieter, Moore, Penny L., Morris, Lynn, Goulder, Philip
Publicado no Sci Transl Med (2016)