Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1

Mutational escape by human immunodeficiency virus (HIV) from cytotoxic T-lymphocyte (CTL) recognition is a major challenge for vaccine design. However, recent studies suggest that CTL escape may carry a sufficient cost to viral replicative capacity to facilitate subsequent immune control of a now at...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Martinez-Picado, Javier, Prado, Julia G., Fry, Elizabeth E., Pfafferott, Katja, Leslie, Alasdair, Chetty, Senica, Thobakgale, Christina, Honeyborne, Isobel, Crawford, Hayley, Matthews, Philippa, Pillay, Tilly, Rousseau, Christine, Mullins, James I., Brander, Christian, Walker, Bruce D., Stuart, David I., Kiepiela, Photini, Goulder, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440414/
https://ncbi.nlm.nih.gov/pubmed/16537629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3617-3623.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados