Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1

Mutational escape by human immunodeficiency virus (HIV) from cytotoxic T-lymphocyte (CTL) recognition is a major challenge for vaccine design. However, recent studies suggest that CTL escape may carry a sufficient cost to viral replicative capacity to facilitate subsequent immune control of a now at...

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Detaylı Bibliyografya
Asıl Yazarlar: Martinez-Picado, Javier, Prado, Julia G., Fry, Elizabeth E., Pfafferott, Katja, Leslie, Alasdair, Chetty, Senica, Thobakgale, Christina, Honeyborne, Isobel, Crawford, Hayley, Matthews, Philippa, Pillay, Tilly, Rousseau, Christine, Mullins, James I., Brander, Christian, Walker, Bruce D., Stuart, David I., Kiepiela, Photini, Goulder, Philip
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440414/
https://ncbi.nlm.nih.gov/pubmed/16537629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3617-3623.2006
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