Control of Human Immunodeficiency Virus Type 1 Is Associated with HLA-B*13 and Targeting of Multiple Gag-Specific CD8(+) T-Cell Epitopes

To better understand relationships between CD8(+) T-cell specificity and the immune control of human immunodeficiency virus type 1 (HIV-1), we analyzed the role of HLA-B*13, an allele associated with low viremia, in a cohort of 578 C clade-infected individuals in Durban, South Africa. Six novel B*13...

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Detalhes bibliográficos
Main Authors: Honeyborne, Isobella, Prendergast, Andrew, Pereyra, Florencia, Leslie, Alasdair, Crawford, Hayley, Payne, Rebecca, Reddy, Shabashini, Bishop, Karen, Moodley, Eshia, Nair, Kriebashnie, van der Stok, Mary, McCarthy, Noel, Rousseau, Christine M., Addo, Marylyn, Mullins, James I., Brander, Christian, Kiepiela, Photini, Walker, Bruce D., Goulder, Philip J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866034/
https://ncbi.nlm.nih.gov/pubmed/17251285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02689-06
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