Proliferative Capacity of Epitope-Specific CD8 T-Cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection

The relationship between the function of human immunodeficiency virus (HIV)-specific CD8 T-cell responses and viral load has not been defined. In this study, we used a panel of major histocompatibility complex class I tetramers to examine responses to frequently targeted CD8 T-cell epitopes in a lar...

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Detalhes bibliográficos
Main Authors: Day, Cheryl L., Kiepiela, Photini, Leslie, Alasdair J., van der Stok, Mary, Nair, Kriebashne, Ismail, Nasreen, Honeyborne, Isobella, Crawford, Hayley, Coovadia, Hoosen M., Goulder, Philip J. R., Walker, Bruce D., Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797250/
https://ncbi.nlm.nih.gov/pubmed/17050606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01754-06
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