Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral...

by Baiyegunhi, Omolara, Ndlovu, Bongiwe, Ogunshola, Funsho, Ismail, Nasreen, Walker, Bruce D., Ndung'u, Thumbi, Ndhlovu, Zaza M.
Published in J Virol (2018)

The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans

by Naidoo, Kewreshini K., Shangase, Zesuliwe B., Rashid, Tabassum, Ngubane, Ayanda, Ismail, Nasreen, Ndung’u, Thumbi, Thobakgale, Christina F.
Published in PLoS One (2020)

HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer(+) Gag-Specific CD4(+) T Cells in Chronic Clade C HIV-1 Infection

by Laher, Faatima, Ranasinghe, Srinika, Porichis, Filippos, Mewalal, Nikoshia, Pretorius, Karyn, Ismail, Nasreen, Buus, Søren, Stryhn, Anette, Carrington, Mary, Walker, Bruce D., Ndung'u, Thumbi, Ndhlovu, Zaza M.
Published in J Virol (2017)

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

by Ogunshola, Funsho, Anmole, Gursev, Miller, Rachel L., Goering, Emily, Nkosi, Thandeka, Muema, Daniel, Mann, Jaclyn, Ismail, Nasreen, Chopera, Denis, Ndung’u, Thumbi, Brockman, Mark A., Ndhlovu, Zaza M
Published in Nat Commun (2018)

Proliferative Capacity of Epitope-Specific CD8 T-Cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection

by Day, Cheryl L., Kiepiela, Photini, Leslie, Alasdair J., van der Stok, Mary, Nair, Kriebashne, Ismail, Nasreen, Honeyborne, Isobella, Crawford, Hayley, Coovadia, Hoosen M., Goulder, Philip J. R., Walker, Bruce D., Klenerman, Paul
Published 2007

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

by Mabuka, Jenniffer M., Dugast, Anne-Sophie, Muema, Daniel M., Reddy, Tarylee, Ramlakhan, Yathisha, Euler, Zelda, Ismail, Nasreen, Moodley, Amber, Dong, Krista L., Morris, Lynn, Walker, Bruce D., Alter, Galit, Ndung’u, Thumbi
Published in Front Immunol (2017)

Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study

by Dong, Krista L, Moodley, Amber, Kwon, Douglas S, Ghebremichael, Musie S., Dong, Mary, Ismail, Nasreen, Ndhlovu, Zaza M, Mabuka, Jenniffer M, Muema, Daniel M, Pretorius, Karyn, Lin, Nina, Walker, Bruce D, Ndung’u, Thumbi
Published in Lancet HIV (2017)

Modeling the temporal dynamics of cervicovaginal microbiota identifies targets that may promote reproductive health

by Munoz, Alexander, Hayward, Matthew R., Bloom, Seth M., Rocafort, Muntsa, Ngcapu, Sinaye, Mafunda, Nomfuneko A., Xu, Jiawu, Xulu, Nondumiso, Dong, Mary, Dong, Krista L., Ismail, Nasreen, Ndung’u, Thumbi, Ghebremichael, Musie S., Kwon, Douglas S.
Published in Microbiome (2021)

CD8(+) T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles

by Koofhethile, Catherine K., Ndhlovu, Zaza M., Thobakgale-Tshabalala, Christina, Prado, Julia G., Ismail, Nasreen, Mncube, Zenele, Mkhize, Lungile, van der Stok, Mary, Yende, Nonhlanhla, Walker, Bruce D., Goulder, Philip J. R., Ndung'u, Thumbi
Published in J Virol (2016)

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective coh...

by Byrne, Elizabeth H, Anahtar, Melis N, Cohen, Kathleen E, Moodley, Amber, Padavattan, Nikita, Ismail, Nasreen, Bowman, Brittany A, Olson, Gregory S, Mabhula, Amanda, Leslie, Alasdair, Ndung’u, Thumbi, Walker, Bruce D, Ghebremichael, Musie S, Dong, Krista L, Kwon, Douglas S
Published in Lancet Infect Dis (2015)

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

by Muema, Daniel M., Akilimali, Ngomu A., Ndumnego, Okechukwu C., Rasehlo, Sipho S., Durgiah, Raveshni, Ojwach, Doty B.A., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Mabuka, Jenniffer M., Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Published in BMC Med (2020)

HIV Control through a Single Nucleotide on the HLA-B Locus

by Kløverpris, Henrik N., Harndahl, Mikkel, Leslie, Alasdair J., Carlson, Jonathan M., Ismail, Nasreen, van der Stok, Mary, Huang, Kuan-Hsiang Gary, Chen, Fabian, Riddell, Lynn, Steyn, Dewald, Goedhals, Dominique, van Vuuren, Cloete, Frater, John, Walker, Bruce D., Carrington, Mary, Ndung'u, Thumbi, Buus, Søren, Goulder, Philip
Published 2012

Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impacts viral set point

by Ndhlovu, Zaza, Kamya, Philomena, Mewalal, Nikoshia, Kløverpris, Henrik N., Nkosi, Thandeka, Pretorius, Karyn, Laher, Faatima, Ogunshola, Funsho, Chopera, Denis, Shekhar, Karthik, Ghebremichael, Musie, Ismail, Nasreen, Moodley, Amber, Malik, Amna, Leslie, Alasdair, Goulder, Philip J.R, Buus, Søren, Chakraborty, Arup, Dong, Krista, Ndung’u, Thumbi, Walker, Bruce D.
Published in Immunity (2015)

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

by Anahtar, Melis N., Byrne, Elizabeth H., Doherty, Kathleen E., Bowman, Brittany A., Yamamoto, Hidemi S., Soumillon, Magali, Padavattan, Nikita, Ismail, Nasreen, Moodley, Amber, Sabatini, Mary E., Ghebremichael, Musie S., Nusbaum, Chad, Huttenhower, Curtis, Virgin, Herbert W., Ndung’u, Thumbi, Dong, Krista L., Walker, Bruce D., Fichorova, Raina N., Kwon, Douglas S.
Published in Immunity (2015)

Lactobacillus-Deficient Cervicovaginal Bacterial Communities are Associated with Increased HIV Acquisition in Young South African Women

by Gosmann, Christina, Anahtar, Melis N., Handley, Scott A., Farcasanu, Mara, Abu-Ali, Galeb, Bowman, Brittany A., Padavattan, Nikita, Desai, Chandni, Droit, Lindsay, Moodley, Amber, Dong, Mary, Chen, Yuezhou, Ismail, Nasreen, Ndung’u, Thumbi, Ghebremichael, Musie S., Wesemann, Duane R., Mitchell, Caroline, Dong, Krista L., Huttenhower, Curtis, Walker, Bruce D., Virgin, Herbert W., Kwon, Douglas S.
Published in Immunity (2017)

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

by Kazer, Samuel W., Aicher, Toby P., Muema, Daniel M., Carroll, Shaina L., Ordovas-Montanes, Jose, Miao, Vincent N., Tu, Ang A., Ziegler, Carly G. K., Nyquist, Sarah K., Wong, Emily B., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Berger, Bonnie, Love, J. Christopher, Dong, Krista L., Leslie, Alasdair, Ndhlovu, Zaza M., Ndung’u, Thumbi, Walker, Bruce D., Shalek, Alex K.
Published in Nat Med (2020)

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

by Millar, Jane R., Bengu, Nomonde, Fillis, Rowena, Sprenger, Ken, Ntlantsana, Vuyokazi, Vieira, Vinicius A., Khambati, Nisreen, Archary, Moherndran, Muenchhoff, Maximilian, Groll, Andreas, Grayson, Nicholas, Adamson, John, Govender, Katya, Dong, Krista, Kiepiela, Photini, Walker, Bruce D., Bonsall, David, Connor, Thomas, Bull, Matthew J., Nxele, Nelisiwe, Roider, Julia, Ismail, Nasreen, Adland, Emily, Puertas, Maria C., Martinez-Picado, Javier, Matthews, Philippa C., Ndung'u, Thumbi, Goulder, Philip
Published in EClinicalMedicine (2020)