Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral...

Por Baiyegunhi, Omolara, Ndlovu, Bongiwe, Ogunshola, Funsho, Ismail, Nasreen, Walker, Bruce D., Ndung'u, Thumbi, Ndhlovu, Zaza M.
Publicado no J Virol (2018)

The DARC-null trait is associated with moderate modulation of NK cell profiles and unaltered cytolytic T cell profiles in black South Africans

Por Naidoo, Kewreshini K., Shangase, Zesuliwe B., Rashid, Tabassum, Ngubane, Ayanda, Ismail, Nasreen, Ndung’u, Thumbi, Thobakgale, Christina F.
Publicado no PLoS One (2020)

HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer(+) Gag-Specific CD4(+) T Cells in Chronic Clade C HIV-1 Infection

Por Laher, Faatima, Ranasinghe, Srinika, Porichis, Filippos, Mewalal, Nikoshia, Pretorius, Karyn, Ismail, Nasreen, Buus, Søren, Stryhn, Anette, Carrington, Mary, Walker, Bruce D., Ndung'u, Thumbi, Ndhlovu, Zaza M.
Publicado no J Virol (2017)

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

Por Ogunshola, Funsho, Anmole, Gursev, Miller, Rachel L., Goering, Emily, Nkosi, Thandeka, Muema, Daniel, Mann, Jaclyn, Ismail, Nasreen, Chopera, Denis, Ndung’u, Thumbi, Brockman, Mark A., Ndhlovu, Zaza M
Publicado no Nat Commun (2018)

Proliferative Capacity of Epitope-Specific CD8 T-Cell Responses Is Inversely Related to Viral Load in Chronic Human Immunodeficiency Virus Type 1 Infection

Por Day, Cheryl L., Kiepiela, Photini, Leslie, Alasdair J., van der Stok, Mary, Nair, Kriebashne, Ismail, Nasreen, Honeyborne, Isobella, Crawford, Hayley, Coovadia, Hoosen M., Goulder, Philip J. R., Walker, Bruce D., Klenerman, Paul
Publicado em 2007

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

Por Mabuka, Jenniffer M., Dugast, Anne-Sophie, Muema, Daniel M., Reddy, Tarylee, Ramlakhan, Yathisha, Euler, Zelda, Ismail, Nasreen, Moodley, Amber, Dong, Krista L., Morris, Lynn, Walker, Bruce D., Alter, Galit, Ndung’u, Thumbi
Publicado no Front Immunol (2017)

Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study

Por Dong, Krista L, Moodley, Amber, Kwon, Douglas S, Ghebremichael, Musie S., Dong, Mary, Ismail, Nasreen, Ndhlovu, Zaza M, Mabuka, Jenniffer M, Muema, Daniel M, Pretorius, Karyn, Lin, Nina, Walker, Bruce D, Ndung’u, Thumbi
Publicado no Lancet HIV (2017)

CD8(+) T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles

Por Koofhethile, Catherine K., Ndhlovu, Zaza M., Thobakgale-Tshabalala, Christina, Prado, Julia G., Ismail, Nasreen, Mncube, Zenele, Mkhize, Lungile, van der Stok, Mary, Yende, Nonhlanhla, Walker, Bruce D., Goulder, Philip J. R., Ndung'u, Thumbi
Publicado no J Virol (2016)

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective coh...

Por Byrne, Elizabeth H, Anahtar, Melis N, Cohen, Kathleen E, Moodley, Amber, Padavattan, Nikita, Ismail, Nasreen, Bowman, Brittany A, Olson, Gregory S, Mabhula, Amanda, Leslie, Alasdair, Ndung’u, Thumbi, Walker, Bruce D, Ghebremichael, Musie S, Dong, Krista L, Kwon, Douglas S
Publicado no Lancet Infect Dis (2015)

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

Por Muema, Daniel M., Akilimali, Ngomu A., Ndumnego, Okechukwu C., Rasehlo, Sipho S., Durgiah, Raveshni, Ojwach, Doty B.A., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Dong, Krista L., Ndhlovu, Zaza M., Mabuka, Jenniffer M., Walker, Bruce D., Mann, Jaclyn K., Ndung’u, Thumbi
Publicado no BMC Med (2020)

HIV Control through a Single Nucleotide on the HLA-B Locus

Por Kløverpris, Henrik N., Harndahl, Mikkel, Leslie, Alasdair J., Carlson, Jonathan M., Ismail, Nasreen, van der Stok, Mary, Huang, Kuan-Hsiang Gary, Chen, Fabian, Riddell, Lynn, Steyn, Dewald, Goedhals, Dominique, van Vuuren, Cloete, Frater, John, Walker, Bruce D., Carrington, Mary, Ndung'u, Thumbi, Buus, Søren, Goulder, Philip
Publicado em 2012

Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impacts viral set point

Por Ndhlovu, Zaza, Kamya, Philomena, Mewalal, Nikoshia, Kløverpris, Henrik N., Nkosi, Thandeka, Pretorius, Karyn, Laher, Faatima, Ogunshola, Funsho, Chopera, Denis, Shekhar, Karthik, Ghebremichael, Musie, Ismail, Nasreen, Moodley, Amber, Malik, Amna, Leslie, Alasdair, Goulder, Philip J.R, Buus, Søren, Chakraborty, Arup, Dong, Krista, Ndung’u, Thumbi, Walker, Bruce D.
Publicado no Immunity (2015)

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

Por Anahtar, Melis N., Byrne, Elizabeth H., Doherty, Kathleen E., Bowman, Brittany A., Yamamoto, Hidemi S., Soumillon, Magali, Padavattan, Nikita, Ismail, Nasreen, Moodley, Amber, Sabatini, Mary E., Ghebremichael, Musie S., Nusbaum, Chad, Huttenhower, Curtis, Virgin, Herbert W., Ndung’u, Thumbi, Dong, Krista L., Walker, Bruce D., Fichorova, Raina N., Kwon, Douglas S.
Publicado no Immunity (2015)

Lactobacillus-Deficient Cervicovaginal Bacterial Communities are Associated with Increased HIV Acquisition in Young South African Women

Por Gosmann, Christina, Anahtar, Melis N., Handley, Scott A., Farcasanu, Mara, Abu-Ali, Galeb, Bowman, Brittany A., Padavattan, Nikita, Desai, Chandni, Droit, Lindsay, Moodley, Amber, Dong, Mary, Chen, Yuezhou, Ismail, Nasreen, Ndung’u, Thumbi, Ghebremichael, Musie S., Wesemann, Duane R., Mitchell, Caroline, Dong, Krista L., Huttenhower, Curtis, Walker, Bruce D., Virgin, Herbert W., Kwon, Douglas S.
Publicado no Immunity (2017)

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

Por Kazer, Samuel W., Aicher, Toby P., Muema, Daniel M., Carroll, Shaina L., Ordovas-Montanes, Jose, Miao, Vincent N., Tu, Ang A., Ziegler, Carly G. K., Nyquist, Sarah K., Wong, Emily B., Ismail, Nasreen, Dong, Mary, Moodley, Amber, Berger, Bonnie, Love, J. Christopher, Dong, Krista L., Leslie, Alasdair, Ndhlovu, Zaza M., Ndung’u, Thumbi, Walker, Bruce D., Shalek, Alex K.
Publicado no Nat Med (2020)

HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE

Por Millar, Jane R., Bengu, Nomonde, Fillis, Rowena, Sprenger, Ken, Ntlantsana, Vuyokazi, Vieira, Vinicius A., Khambati, Nisreen, Archary, Moherndran, Muenchhoff, Maximilian, Groll, Andreas, Grayson, Nicholas, Adamson, John, Govender, Katya, Dong, Krista, Kiepiela, Photini, Walker, Bruce D., Bonsall, David, Connor, Thomas, Bull, Matthew J., Nxele, Nelisiwe, Roider, Julia, Ismail, Nasreen, Adland, Emily, Puertas, Maria C., Martinez-Picado, Javier, Matthews, Philippa C., Ndung'u, Thumbi, Goulder, Philip
Publicado no EClinicalMedicine (2020)