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HIV Control through a Single Nucleotide on the HLA-B Locus
Genetic variation within the HLA-B locus has the strongest impact on HIV disease progression of any polymorphisms within the human genome. However, identifying the exact mechanism involved is complicated by several factors. HLA-Bw4 alleles provide ligands for NK cells and for CD8 T cells, and strong...
Gorde:
Egile Nagusiak: | , , , , , , , , , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Microbiology
2012
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3486337/ https://ncbi.nlm.nih.gov/pubmed/22896606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01020-12 |
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