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HLA-A*68:02-restricted Gag-specific CTL responses can drive selection pressure on HIV but are subdominant and ineffective
BACKGROUND: HLA class I polymorphism has the greatest impact of human genetic variation on viral load set point. A substantial part of this effect is due to the action of HLA-B and HLA-C alleles. With few exceptions the role of HLA-A molecules in immune control of HIV is unclear. METHODS: We here st...
Tallennettuna:
| Julkaisussa: | AIDS |
|---|---|
| Päätekijät: | , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6315297/ https://ncbi.nlm.nih.gov/pubmed/23525031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32836146cd |
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