CD8(+) T-cell receptor bias and immundominance in HIV-1 infection

Immunodominance describes a phenomenon whereby the immune system consistently targets only a fraction of the available antigen pool derived from a given pathogen. In the case of CD8(+) T-cells, these constrained epitope targeting patterns are linked to human leukocyte antigen (HLA) class-I expressio...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Kløverpris, Henrik N., McGregor, Reuben, McLaren, James E., Ladell, Kristin, Harndahl, Mikkel, Stryhn, Anette, Carlson, Jonathan, Koofhethile, Catherine, Gerritsen, Bram, Kesmir, Can, Chen, Fabian, Riddell, Lynn, Luzzi, Graz, Leslie, Alasdair, Walker, Bruce D., Ndung'u, Thumbi, Buus, Søren, Price, David A., Goulder, Philip J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433859/
https://ncbi.nlm.nih.gov/pubmed/25911754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400854
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