Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

Some closely related human leukocyte antigen (HLA) alleles are associated with variable clinical outcomes following HIV-1 infection despite presenting the same viral epitopes. Mechanisms underlying these differences remain unclear but may be due to intrinsic characteristics of the HLA alleles or res...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ogunshola, Funsho, Anmole, Gursev, Miller, Rachel L., Goering, Emily, Nkosi, Thandeka, Muema, Daniel, Mann, Jaclyn, Ismail, Nasreen, Chopera, Denis, Ndung’u, Thumbi, Brockman, Mark A., Ndhlovu, Zaza M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258674/
https://ncbi.nlm.nih.gov/pubmed/30479346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07209-7
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