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Impact of HLA-B*81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity
HIV-1 attenuation resulting from immune escape mutations selected in Gag may contribute to slower disease progression in HIV-1-infected individuals expressing certain HLA class I alleles. We previously showed that the protective allele HLA-B*81 and the HLA-B*81-selected Gag T186S mutation are strong...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3302318/ https://ncbi.nlm.nih.gov/pubmed/22238317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06682-11 |
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