Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

In the large majority of cases, HIV infection is established by a single variant, and understanding the characteristics of successfully transmitted variants is relevant to prevention strategies. Few studies have investigated the viral determinants of mother-to-child transmission. To determine the im...

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Foilsithe in:J Virol
Main Authors: Naidoo, Vanessa L., Mann, Jaclyn K., Noble, Christie, Adland, Emily, Carlson, Jonathan M., Thomas, Jake, Brumme, Chanson J., Thobakgale-Tshabalala, Christina F., Brumme, Zabrina L., Brockman, Mark A., Goulder, Philip J. R., Ndung'u, Thumbi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2017
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553170/
https://ncbi.nlm.nih.gov/pubmed/28637761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00518-17
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