Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

In the large majority of cases, HIV infection is established by a single variant, and understanding the characteristics of successfully transmitted variants is relevant to prevention strategies. Few studies have investigated the viral determinants of mother-to-child transmission. To determine the im...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Naidoo, Vanessa L., Mann, Jaclyn K., Noble, Christie, Adland, Emily, Carlson, Jonathan M., Thomas, Jake, Brumme, Chanson J., Thobakgale-Tshabalala, Christina F., Brumme, Zabrina L., Brockman, Mark A., Goulder, Philip J. R., Ndung'u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553170/
https://ncbi.nlm.nih.gov/pubmed/28637761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00518-17
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