Influence of Gag-Protease-Mediated Replication Capacity on Disease Progression in Individuals Recently Infected with HIV-1 Subtype C

HLA class I-mediated selection of immune escape mutations in functionally important Gag epitopes may partly explain slower disease progression in HIV-1-infected individuals with protective HLA alleles. To investigate the impact of Gag function on disease progression, the replication capacities of vi...

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Detalhes bibliográficos
Main Authors: Wright, Jaclyn K., Novitsky, Vladimir, Brockman, Mark A., Brumme, Zabrina L., Brumme, Chanson J., Carlson, Jonathan M., Heckerman, David, Wang, Bingxia, Losina, Elena, Leshwedi, Mopo, van der Stok, Mary, Maphumulo, Lungile, Mkhwanazi, Nompumelelo, Chonco, Fundisiwe, Goulder, Philip J. R., Essex, Max, Walker, Bruce D., Ndung'u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126116/
https://ncbi.nlm.nih.gov/pubmed/21289112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02520-10
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